The pursuit of Moore’s Law is slowing and the exploration of alternative devices is underway to replace the CMOS transistor and traditional architectures at the heart of data processing. Moreover, the emergence of stringent application constraints, particularly those linked to energy consumption, require new system architectural strategies (e.g. manycore) and real-time operational adaptability approaches. Such complex systems require new and powerful design and programming methods to ensure optimal and reliable operation. This special issue aims at collating new research along all the dimensions of emerging technologies and architectures for computing in manycores.